Our goal is to assess the combination of Cell Painting, transcriptomics and proteomics in a variety of cell models for safety assessment, using hepatotoxicity as test case 

About Us

At a Glance:

The ‘Omics for Assessing Signatures for Integrated Safety (OASIS) Consortium was officially convened in July 2023 between the non-profit Health and Environmental Sciences Institute (HESI) and the Broad Institute of Harvard and MIT. The Consortium is supported by an award from the Massachusetts Life Sciences Center (MLSC), in synergy with partnered resources and expertise from industry partners and in-kind contributions from academic, government, NGO, and biotech partners. This exciting effort engages >60 global experts in toxicology, cell biology, bioinformatics, risk assessment, and assay development from more from 15 academic institutes, 7 government agencies, 17 industry organizations, and 4 non-government organizations. 

 

Leadership

Co-Chairs

Dr. Anne Carpenter
Dr. Anne Carpenter
Broad Institute
Dr. David Rouquie
Dr. David Rouquie
Bayer Crop Science

Data Analysts

Dr. Srijit Seal
Dr. Srijit Seal
Broad Institute
Dr. Jessica Ewald
Dr. Jessica Ewald
Broad Institute
Jonne Reitdijk
Jonne Reitdijk
Broad Institute
Runxi Shen
Runxi Shen
Broad Institute

Steering Committee

Dr. Shantanu Singh
Dr. Shantanu Singh
Broad Institute
Dr. Jess LaRocca
Dr. Jess LaRocca
Corteva
Dr. Josh Harrill
Dr. Josh Harrill
EPA
Dr. Andreas Bender
Dr. Andreas Bender
Cambridge University
Dr. Aaron Fullerton
Dr. Aaron Fullerton
Genentech
Dr. Sabah Kadri
Dr. Sabah Kadri
AbbVie
Dr. Nicole Kleinstreuer
Dr. Nicole Kleinstreuer
NIEHS
Dr. Nynke Kramer
Dr. Nynke Kramer
Wageningen University
Dr. Deidre Dalmas
Dr. Deidre Dalmas
Chrissy Crute, PhD
Chrissy Crute, PhD
HESI Global
Connie Mitchell, MS
Connie Mitchell, MS
HESI Global